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iTIVA is a pharmacokinetic/pharmacodynamic simulation App that provides information about the distribution of drugs based on mathematical models and simulates the behavior of a TCI (Target Controlled Infusion) pump calculating infusion rates to reach and maintain a set target effect-site concentration. Those schemes can be implemented in volumetric infusion pumps and be guided with pharmacokinetics models, to do "manual TCI" or target guided infusions. Pharmacokinetic models iTIVA includes a library with 25 drugs and more than 55 pharmacokinetic models, that are updated continuously when you subscribe*: - Remifentanil (ULTIVA) - Fentanyl - Sufentanil - Alfentanil - Hydromorphone - Morphine - Ketamine - Procaine - Lidocaine - Propofol (DIPRIVAN) - Dexmedetomidine (PRECEDEX) - Midazolam - Thiopental - Atracurium - Cisatracurium - Rocuronium - Vecuronium - Tranexamic - Magnesium sulfate - Diazepam - Heparin - ACT estimation - Protamine This app also calculates the end-tidal (Et) concentration for a set MAC age for Isoflurane, Sevoflurane, and Desflurane, using the Mapleson equation. - Record intraoperative milestones (like unconsciousness, BIS value, etc..) - Share your case with other colleagues using QR codes - Export all recorded information as an excel file -------- *iTIVA full access for a year Additional features are available when you subscribe to iTIVA yearly, this optional paid subscription service funds the app’s development and allows full access to the main features of this App: - Access to new PK / PD models published in the literature that are updated as they become available. - Ask to include new models - Simulates up to 7 drug drugs at a time - Unlimited simulations without time restriction - Export your case data to an XLS file - 24 hrs support iTIVA's yearly subscription is available for US$9,99/year. The subscription will be charged to iTunes Account at confirmation of purchase • Subscription automatically renews unless auto-renew is turned off at least 24-hours before the end of the current period • The account will be charged for renewal within 24-hours before the end of the current period, and identify the cost of the renewal • Subscriptions may be managed by the user and auto-renewal may be turned off by going to the user's Account Settings after purchase • Any unused portion of a free trial period, if offered, will be forfeited when the user purchases a subscription to that publication, where applicable More details can be found here iTIVA Privacy Policy: https://itiva.co/privacy.html Terms and Conditions: http://itiva.co/terms.html