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All the authority of the most trusted brand in medical content in a convenient, portable guide Derived from most clinically salient content featured in Harrison's Principles of Internal Medicine, 20th Edition, this full color, the portable guide covers all diseases and conditions commonly seen in general medical practice. This edition has been updated to reflect the latest clinical developments in medicine. Designed for quick access and employing an effective blend of concise text, bulleted key points, decision trees, and summary tables, the Manual makes it easy to find what you need at the point of care. The easy-to-navigate chapters use a standard repeating template: KEY FEATURES * Etiology and Epidemiology * Clinically Relevant Pathophysiology * Signs and Symptoms * Differential Diagnosis * Physical and Laboratory Findings * Therapeutics * Practice Guidelines, and more Editors: J. Larry Jameson, MD, PhD Robert G. Dunlop Professor of Medicine Dean, Raymond and Ruth Perelman School of Medicine Executive Vice President, University of Pennsylvania for the Health System Philadelphia, Pennsylvania Anthony S. Fauci, MD Chief, Laboratory of Immunoregulation Director, National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda, Maryland Dennis L. Kasper, MD William Ellery Channing Professor of Medicine Professor of Immunology Department of Immunology Harvard Medical School Boston, Massachusetts Stephen L. Hauser, MD Robert A. Fishman Distinguished Professor Department of Neurology Director, UCSF Weill Institute for Neurosciences University of California, San Francisco San Francisco, California Dan L. Longo, MD Professor of Medicine Harvard Medical School Senior Physician, Brigham and Women’s Hospital Deputy Editor, New England Journal of Medicine Boston, Massachusetts Joseph Loscalzo, MD, PhD Hersey Professor of the Theory and Practice of Medicine Harvard Medical School Chairman, Department of Medicine Physician-in-Chief, Brigham and Women’s Hospital Boston, Massachusetts