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The CUT score is a new cancer risk score for thyroid nodules suitable in any clinical setting. The CUT is an acronym indicating Clinical, Ultrasonographic and Thyroid cytology aspects of a thyroid nodule. The CUT score has been created to help clinicians with thyroid nodule preoperative malignancy risk assessment. This tool is intentionally developed on easily avalaible clinical data in order to allow physicians to apply the ‘‘CUT’’ score in any clinical setting using basic US technology. In the CUT score, the sum of each clinical (C) and/or ultrasonographic (U) suspicious feature results in the C+U sum, ranging from 0 to 10. This sum along with the five-tiered score of the fine-needle aspiration results (T = 1–5) determines the final ‘‘CUT’’ score of the TN. The C+U sum of the CUT score: helps to select thyroid nodules requiring fine-needle aspiration (e.g., the thyroid nodule with the highest C+U score in a multinodular goiter) when the thyroid cytology (T) is avalaible, allows to assess the risk of malignancy of the thyroid nodule in the final CUT score. The CUT score is designated exclusively for medical use and is not intended to be directly used by the patient to take any medical decision without a doctor’s advice. It has been created by the work of endocrinologists operating in the Policlinico Gemelli’s Division of Endocrinology. It’s a medical application derived from the following published studies: Campanella P, Ianni F, Rota CA, Corsello SM, Pontecorvi A. Quantification of cancer risk of each clinical and ultrasonographic suspicious feature of thyroid nodules: a systematic review and meta-analysis. Eur J Endocrinol. 2014 Apr 10;170(5):R203-11. doi: 10.1530/EJE-13-0995. Ianni F, Campanella P, Rota CA, Prete A, Castellino L, Pontecorvi A, Corsello SM. A meta-analysis-derived proposal for a clinical, ultrasonographic, and cytological scoring system to evaluate thyroid nodules: the "CUT" score. Endocrine. 2015 Oct 30. Ianni F, Pascucci D, Paragliola RM, Rota CA, Perotti G, Fadda G, Pontecorvi A, Corsello SM. Follow-up or Surgery for Indeterminate Thyroid Nodules: Could the CUT Score Application Be a Support for Decision-Making in the Preoperative Assessment? Thyroid. 2019 Oct 23. doi: 10.1089/thy.2018.0649.
